ABCE1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14458

Overview

Synonyms 2' 5' oligoadenylate binding protein,2''-5''-oligoadenylate-binding protein,2'5' oligoadenylate binding protein,ABC 38,ABC38,ABCE 1,ABCE1,ABCE1,ATP binding cassette sub family E (OABP) member 1,ATP binding cassette sub family E member 1,ATP-binding cassette sub-family E member 1,HuHP 68,HuHP68,OABP,Ribonuclease 4 inhibitor,Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L inhibitor,RLI,RNase L inhibitor,RNASEL1,RNASELI,RNS 4I,RNS4I
Swissprot P61221
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human ABCE1
Application WB,ELISA
Recommended dilution WB 1:500-1:2000
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

 

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