ABCG5 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-12688

Overview

Synonyms Abcg5,ABCG5,ATP binding cassette sub family G (WHITE) member 5 (sterolin 1),ATP binding cassette sub family G member 5,ATP-binding cassette sub-family G member 5,ATP-binding cassette,sub-family G (WHITE),member 5,Sterolin 1,Sterolin-1,STSL
Swissprot Q9H222
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human ABCG5
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

 

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