ACP6 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15175

Overview

Synonyms Acid phosphatase 6,Acid phosphatase 6,lysophosphatidic,Acid phosphatase like 1,Acid phosphatase like protein 1,Acid phosphatase-like protein 1,ACP6,ACPL1,LPAP,Lysophosphatidic acid phosphatase 6,Lysophosphatidic acid phosphatase type 6,Lysophosphatidic acid phosphatase type 6 precursor,lysophosphatidic,PACPL1,PPA6
Swissprot Q9NPH0
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human ACP6
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

 

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