ADAMTS10 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-12944

Overview

Synonyms A disintegrin and metalloproteinase with thrombospondin motifs 10,A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif,10,A disintegrin-like and metallopeptidase with thrombospondin type 1 motif,10,ADAM metallopeptidase with thrombospondin type 1 motif 10,ADAM TS10,ADAM-TS 10,ADAM-TS10,ADAMTS-10,Adamts10,ATS10,EC 3.4.24,WMS,WMS1,zinc metalloendopeptidase
Swissprot Q9H324
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human ADAMTS10
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.

 

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