ADPRHL2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-12993

Overview

Synonyms [Protein ADP ribosylarginine] hydrolase like protein 2,[Protein ADP-ribosylarginine] hydrolase-like protein 2,ADP ribosylhydrolase 3,ADP ribosylhydrolase like 2,ADP-ribosylhydrolase 3,Adprhl2,AI836109,ARH3,ARHL2,ecto ADP ribosylhydrolase,FLJ20446,OTTMUSP00000009757,Poly(ADP ribose) glycohydrolase ARH3,Poly(ADP-ribose) glycohydrolase ARH3,Protein ADP ribosylarginine hydrolase like protein 2,RP23-113P22.3
Swissprot Q9NX46
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human ADPRHL2
Application WB,ELISA
Recommended dilution WB 1:200-1:1000
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.

 

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