AKR1D1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14530

Overview

Synonyms 3-oxo-5-beta-steroid 4-dehydrogenase,3o5bred,AK1D1,AKR1D1,aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase),Aldo keto reductase family 1 member D1,Aldo-keto reductase family 1 member D1,CBAS2,Delta(4) 3 ketosteroid 5 beta reductase,Delta(4) 3 oxosteroid 5 beta reductase,Delta(4)-3-ketosteroid 5-beta-reductase,Delta(4)-3-oxosteroid 5-beta-reductase,SRD5B1,steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1),steroid 5 beta reductase
Swissprot P51857
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human AKR1D1
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
Concentration 0.1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

 

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