AKR7A2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60266

Overview

Synonyms AFAR,AFAR1,AFB1 aldehyde reductase 1,AFB1 AR1,AFB1-AR 1,AFB1AR1,Aflatoxin aldehyde reductase,Aflatoxin B1 aldehyde reductase member 2,Aflatoxin beta1 aldehyde reductase,Aiar,AKR7,Akr7a2,Aldo keto reductase family 7,Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase,Aldo keto reductase family 7 member A2,Aldo keto reductase family 7,member A2 (aflatoxin aldehyde reductase),Aldoketoreductase 7,ARK72,SSA reductase,Succinic semialdehyde reductase
Swissprot O43488
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human AKR7A2
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

 

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