AMIGO2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10790


Synonyms Adhesion molecule with Ig like domain 2,ALI 1,ALI1,Alivin 1,Alivin-1,Alivin1,AMGO2,AMIGO 2,AMIGO-2,Amigo2,Amphoterin induced gene 2,Amphoterin induced protein 2,Amphoterin-induced gene and open reading frame 2,Amphoterin-induced protein 2,DEGA,Differentially expressed in gastric adenocarcinoma,Differentially expressed in gastric adenocarcinomas,Transmembrane protein AMIGO 2,Transmembrane protein AMIGO2
Swissprot Q86SJ2
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human AMIGO2
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.5mg/mL
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction


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