ANAPC4 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-12723

Overview

Synonyms ANAPC 4,anapc4,Anaphase Promoting Complex Subunit 4,Anaphase-promoting complex subunit 4,APC 4,APC Complex Protein CUT20,APC4,APC4,CUT20,Cyclosome subunit 4,LID1
Swissprot Q9UJX5
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human ANAPC4
Application WB,IHC,ELISA
Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. 

 

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