ANP32E Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16557

Overview

Synonyms Acidic (leucine rich) nuclear phosphoprotein 32 family member E,Acidic leucine-rich nuclear phosphoprotein 32 family member E,AN32E,anp32e,Cerebellar postnatal development protein 1,LANP like protein,LANP-L,LANP-like protein,LANPL,Leucine rich acidic nuclear protein like,MGC5350
Swissprot Q9BTT0
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human ANP32E
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The Anp32 family consists of 32 evolutionarily-conserved proteins and is included within the superfamily of leucine-rich repeat (LRR) proteins. Leucine-rich acidic nuclear protein-like (LANPL), also called ANP32E or Cpd1, is a member of the Anp32 family. LANPL is located in the cytoplasm of peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It has also been detected in the nucleus, cytoplasm and membrane of multiple brain regions. Upon phosphorylation, LANPL colocalizes and inhibits protein phosphatase 2A (PP2A), but does not inhibit PP1. LANPL modulates cell signalling and transduction of gene expression to regulate the morphology and dynamics of the cytoskeleton, cell adhesion, neural development and cerebellar morphogenesis.

 

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