Anti-AADAT Antibody

Rs. 45,619.00
SKU stj115056

General Information

Product name Anti-AADAT Antibody
Short Description Rabbit polyclonal to AADAT
Description This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:1000 - 1:2000
Protein Name Kynurenine/alpha-aminoadipate aminotransferasemitochondrialKAT/AadAT2-aminoadipate aminotransferase2-aminoadipate transaminase
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_001273611.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 47.4 kDa
Database Links
Alternative Names AADATKynurenine/alpha-aminoadipate aminotransferase antibodymitochondrial antibodyKAT/AadAT antibody2-aminoadipate aminotransferase antibody2-aminoadipate transaminaseAADAT antibodyKAT2
Function Transaminase with broad substrate specificity, Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate, Shows activity also towards tryptophan, aspartate and hydroxykynurenine, Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid, Can also use glyoxylate as amino-group acceptor (in vitro).
Cellular Localization Mitochondrion
Tissue Specificity Higher expression in the liver, also found in heart, brain, kidney, pancreas, prostate, testis and ovary
Swiss-Prot Key

 

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