Anti-ABCA1 Antibody

Rs. 45,619.00
SKU stj29308

General Information

Product name Anti-ABCA1 Antibody
Short Description Rabbit polyclonal to ABCA1
Description The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ABCA1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1 (NP_005493.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 254.3 kDa
Database Links
Alternative Names ABCA1ATP-binding cassette sub-family A member 1 antibodyATP-binding cassette transporter 1 antibodyABC-1 antibodyATP-binding cassette 1 antibodyCholesterol efflux regulatory proteinABCA1 antibodyABC1 antibodyCERP
Function cAMP-dependent and sulfonylurea-sensitive anion transporter, Key gatekeeper influencing intracellular cholesterol transport
Cellular Localization Membrane
Tissue Specificity Widely expressed, but most abundant in macrophages
Swiss-Prot Key

 

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