Anti-ABCA3 Antibody

Rs. 45,619.00
SKU stj28942

General Information

Product name Anti-ABCA3 Antibody
Short Description Rabbit polyclonal to ABCA3
Description The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-ABCA3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 43-203 of human ABCA3 (NP_001080.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 191.4 kDa
Database Links
Alternative Names ABCA3ATP-binding cassette sub-family A member 3 antibodyABC-C transporter antibodyATP-binding cassette transporter 3 antibodyATP-binding cassette 3ABCA3 antibodyABC3
Function Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol
Cellular Localization Membrane
Tissue Specificity Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart, weakly expressed in placenta, kidney and liver, also expressed in medullary thyroid carcinoma cells (mtc) and in c-cell carcinoma
Swiss-Prot Key

 

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