Anti-ABCB5 Antibody

Rs. 57,098.00
SKU stj72665

General Information

Product name Anti-ABCB5 Antibody
Short Description Goat polyclonal to ABCB5
Description
Applications ELISA
Dilution range
Protein Name Anti-ABCB5 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 138.6 kDa
Database Links
Alternative Names ABCB5ATP-binding cassette sub-family B member 5 antibodyABCB5 P-gp antibodyP-glycoprotein ABCB5ABCB5
Function Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation, Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin, Specifically present in limbal stem cells, where it plays a key role in corneal development and repair,
Cellular Localization Cell membrane
Tissue Specificity Expressed by cd133-expressing progenitor cells among epidermal melanocytes (at protein level), widely expressed with specific expression in pigment cells, highly expressed in several malignant tissues: highly expressed in clinical melanomas, with low expression in normal skin, in melanoma, marks malignant melanoma-initiating cells (mmic), in which clinical virulence resides as a consequence of unlimited self-renewal capacity, resulting in inexorable tumor progression and metastasis, also highly expressed in a number of leukemia cells, expressed in basal limbal epithelium,
Swiss-Prot Key

 

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