Anti-ABCC1 Antibody

Rs. 45,619.00
SKU stj22459

General Information

Product name Anti-ABCC1 Antibody
Short Description Rabbit polyclonal to ABCC1
Description The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ABCC1 Antibody
Immunogen A synthetic peptide of human ABCC1
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 171.6 kDa
Database Links
Alternative Names ABCC1Multidrug resistance-associated protein 1 antibodyATP-binding cassette sub-family C member 1 antibodyLeukotriene C(4 antibodytransporter antibodyLTC4 transporterABCC1 antibodyMRP antibodyMRP1
Function Mediates export of organic anions and drugs from the cytoplasm, Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics, Confers resistance to anticancer drugs, Hydrolyzes ATP with low efficiency.
Cellular Localization Cell membrane
Tissue Specificity Lung, testis and peripheral blood mononuclear cells
Swiss-Prot Key

 

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