Anti-ABO Antibody

Rs. 45,619.00
SKU stj22473

General Information

Product name Anti-ABO Antibody
Short Description Rabbit polyclonal to ABO
Description This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-ABO Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 54-354 of human ABO (NP_065202.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 40.9 kDa
Database Links
Alternative Names ABOHisto-blood group ABO system transferase antibodyFucosylglycoprotein 3-alpha-galactosyltransferase antibodyFucosylglycoprotein alpha-N-acetylgalactosaminyltransferase antibodyGlycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferaseABO
Function This protein is the basis of the ABO blood group system, The histo-blood group ABO involves three carbohydrate antigens: A, B, and H, A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity
Cellular Localization Golgi apparatus, Golgi stack membrane
Tissue Specificity
Swiss-Prot Key

 

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