Anti-AcetylH3K27ac-(K27) Antibody

Rs. 50,211.00
SKU stj29395

General Information

Product name Anti-AcetylH3K27ac-(K27) Antibody
Short Description Rabbit polyclonal to AcetylH3K27ac(K27)
Description Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Applications WB,IHC,IF,IP,ChIP,ChIP
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
ChIP 1:20 - 1:100
CHIPseq 1:20 - 1:100
Protein Name Anti-AcetylH3K27ac-(K27) Antibody
Immunogen A synthetic acetylated peptide corresponding to residues surrounding K27 of human Histone H3
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 15.5 kDa
Database Links
Alternative Names HIST3H3Histone H3.1t antibodyH3/t antibodyH3t antibodyH3/gHIST3H3 antibodyH3FT
Function Core component of nucleosome, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Cellular Localization Nucleus, Chromosome
Tissue Specificity Expressed in testicular cells
Swiss-Prot Key

 

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