General Information
| Product name | Anti-ACSVL6 antibody |
|---|---|
| Short Description | |
| Description | Rabbit polyclonal to ACSVL6. |
| Applications | WB,IHC,IF,ELISA |
| Dilution range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Protein Name | Anti-ACSVL6 antibody |
| Immunogen | Synthesized peptide derived from human ACSVL6 |
| Storage Instruction | Store at -20°C, and avoid repeat freeze-thaw cycles. |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 75 kDa |
| Database Links | |
| Alternative Names | Bile acyl-CoA synthetase antibody BACS antibody Bile acid-CoA ligase antibody BA-CoA ligase antibody BAL antibody Cholate--CoA ligase antibody Fatty acid transport protein 5 antibody FATP-5 antibody Fatty-acid-coenzyme A ligase, very long-chain 3 antibody Solute carrier family 27 member 5 antibody Very long-chain acyl-CoA synthetase homolog 2 antibody VLCS-H2 antibody VLCSH2 antibody Very long-chain acyl-CoA synthetase-related protein antibody VLACS-related antibody VLACSR antibody ACSB antibody FACVL3 antibody FATP5 antibody |
| Function | Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. |
| Cellular Localization | Endoplasmic reticulum membrane |
| Tissue Specificity | Predominantly expressed in liver. |
| Swiss-Prot Key |