Anti-ACTL7B Antibody

Rs. 45,619.00
SKU stj115115

General Information

Product name Anti-ACTL7B Antibody
Short Description Rabbit polyclonal to ACTL7B
Description The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
Applications WB
Dilution range WB 1:1000 - 1:2000
Protein Name Actin-like protein 7BActin-like-7-beta
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human ACTL7B (NP_006677.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 45.2 kDa
Database Links
Alternative Names ACTL7BActin-like protein 7B antibodyActin-like-7-betaACTL7B
Function
Cellular Localization Cytoplasm, cytoskeleton
Tissue Specificity Detected only in the testis and, to a lesser extent, in the prostate.
Swiss-Prot Key

 

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