Anti-ACTN2 Antibody

Rs. 45,619.00
SKU stj22501

General Information

Product name Anti-ACTN2 Antibody
Short Description Rabbit polyclonal to ACTN2
Description Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-ACTN2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ACTN2 (NP_001094.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 103.9 kDa
Database Links
Alternative Names ACTN2Alpha-actinin-2 antibodyAlpha-actinin skeletal muscle isoform 2 antibodyF-actin cross-linking proteinACTN2
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures, This is a bundling protein
Cellular Localization Cytoplasm, myofibril, sarcomere, Z line.
Tissue Specificity Expressed in both skeletal and cardiac muscle
Swiss-Prot Key

 

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