Anti-ADAM11 Antibody

Rs. 45,619.00
SKU stj116462

General Information

Product name Anti-ADAM11 Antibody
Short Description Rabbit polyclonal to ADAM11
Description This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Disintegrin and metalloproteinase domain-containing protein 11ADAM 11Metalloproteinase-likedisintegrin-likeand cysteine-rich proteinMDC
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 290-430 of human ADAM11 (NP_002381.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 83.4 kDa
Database Links
Alternative Names ADAM11Disintegrin and metalloproteinase domain-containing protein 11 antibodyADAM 11 antibodyMetalloproteinase-like antibodydisintegrin-like antibodyand cysteine-rich protein antibodyMDCADAM11 antibodyMDC
Function Probable ligand for integrin in the brain, This is a non catalytic metalloprotease-like protein
Cellular Localization Membrane
Tissue Specificity Expressed predominantly in brain, slightly detected or not at all in other tissues
Swiss-Prot Key

 

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