Anti-CD97 Antibody

Rs. 45,619.00
SKU stj23018

General Information

Product name Anti-CD97 Antibody
Short Description Rabbit polyclonal to ADGRE5
Description This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
Applications WB,IHC
Dilution range WB 1:200 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-CD97 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 240-435 of human CD97 (NP_001775.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 91.9 kDa
Database Links
Alternative Names ADGRE5CD97 antigen antibodyLeukocyte antigen CD97 antibodyCD antigen CD97CD97
Function Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation, Plays an essential role in leukocyte migration (By similarity).
Cellular Localization Cell membrane
Tissue Specificity Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes, expressed also abundantly by smooth muscle cells, expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too, expression are increased under inflammatory conditions in the cns of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis, increased expression of cd97 in the synovium is accompanied by detectable levels of soluble cd97 in the synovial fluid
Swiss-Prot Key

 

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