Anti-ADM antibody

Rs. 50,211.00
SKU stj91501

General Information

Product name Anti-ADM antibody
Short Description
Description Rabbit polyclonal to ADM.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-ADM antibody
Immunogen Synthesized peptide derived from human ADM.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 20 kDa
Database Links
Alternative Names ADM antibody
Adrenomedullin antibody
AM antibody
Proadrenomedullin N-20 terminal peptide antibody
ProAM N-terminal 20 peptide antibody
PAMP antibody
ProAM-N20 antibody
AM antibody
Function AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Cellular Localization Secreted.
Tissue Specificity Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed