Anti-ADNP Antibody

Rs. 45,619.00
SKU stj22524

General Information

Product name Anti-ADNP Antibody
Short Description Rabbit polyclonal to ADNP
Description Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ADNP Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 843-1102 of human ADNP (NP_056154.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 123.6 kDa
Database Links
Alternative Names ADNPActivity-dependent neuroprotector homeobox protein antibodyActivity-dependent neuroprotective proteinADNP antibodyADNP1 antibodyKIAA0784
Function Potential transcription factor, May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation
Cellular Localization Nucleus
Tissue Specificity Widely expressed, strong expression in heart, skeletal muscle, kidney and placenta, in brain, expression is stronger in the cerebellum and cortex regions, no expression detected in the colon, strong increase of expression in colon and breast cancer tissues
Swiss-Prot Key

 

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