Anti-ADORA2A Antibody

Rs. 45,619.00
SKU stj22527

General Information

Product name Anti-ADORA2A Antibody
Short Description Rabbit polyclonal to ADORA2A
Description This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-ADORA2A Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ADORA2A (NP_000666.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 44.7 kDa
Database Links
Alternative Names ADORA2AAdenosine receptor A2aADORA2A antibodyADORA2
Function Receptor for adenosine, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase
Cellular Localization Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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