Anti-ADRA2A Antibody

Rs. 45,619.00
SKU stj115876

General Information

Product name Anti-ADRA2A Antibody
Short Description Rabbit polyclonal to ADRA2A
Description Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Alpha-2A adrenergic receptorAlpha-2 adrenergic receptor subtype C10Alpha-2A adrenoreceptorAlpha-2A adrenoceptorAlpha-2AAR
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRA2A (NP_000672.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 49 kDa
Database Links
Alternative Names ADRA2AAlpha-2A adrenergic receptor antibodyAlpha-2 adrenergic receptor subtype C10 antibodyAlpha-2A adrenoreceptor antibodyAlpha-2A adrenoceptor antibodyAlpha-2AARADRA2A antibodyADRA2R antibodyADRAR
Function Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins, The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine, For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
Cellular Localization Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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