Anti-ADRM1 Antibody

Rs. 45,619.00
SKU stj22536

General Information

Product name Anti-ADRM1 Antibody
Short Description Rabbit polyclonal to ADRM1
Description This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:1000 - 1:4000
Protein Name Anti-ADRM1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 108-407 of human ADRM1 (NP_008933.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 42.2 kDa
Database Links
Alternative Names ADRM1Proteasomal ubiquitin receptor ADRM1 antibody110 kDa cell membrane glycoprotein antibodyGp110 antibodyAdhesion-regulating molecule 1 antibodyARM-1 antibodyProteasome regulatory particle non-ATPase 13 antibodyhRpn13 antibodyRpn13 homologADRM1 antibodyGP110
Function Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins, This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required, Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair, Within the complex, functions as a proteasomal ubiquitin receptor, Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation, UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed