Anti-AFP Antibody

Rs. 45,619.00
SKU stj113435

General Information

Product name Anti-AFP Antibody
Short Description Mouse monoclonal to AFP
Description This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Applications WB,IF,FC
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
FC 1:20 - 1:50
Protein Name Alpha-fetoproteinAlpha-1-fetoproteinAlpha-fetoglobulin
Immunogen Recombinant protein of human AFP
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Mouse
Clonality Monoclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 68.7 kDa
Database Links
Alternative Names AFPAlpha-fetoprotein antibodyAlpha-1-fetoprotein antibodyAlpha-fetoglobulinAFP antibodyHPAFP
Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin, Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties
Cellular Localization Secreted
Tissue Specificity Plasma, synthesized by the fetal liver and yolk sac
Swiss-Prot Key

 

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