Anti-AGFG1 Antibody

Rs. 45,619.00
SKU stj115461

General Information

Product name Anti-AGFG1 Antibody
Short Description Rabbit polyclonal to AGFG1
Description The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Arf-GAP domain and FG repeat-containing protein 1HIV-1 Rev-binding proteinNucleoporin-like protein RIPRev-interacting proteinRev/Rex activation domain-binding protein
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human AGFG1 (NP_004495.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 58.3 kDa
Database Links
Alternative Names AGFG1Arf-GAP domain and FG repeat-containing protein 1 antibodyHIV-1 Rev-binding protein antibodyNucleoporin-like protein RIP antibodyRev-interacting protein antibodyRev/Rex activation domain-binding proteinAGFG1 antibodyHRB antibodyRAB antibodyRIP
Function Required for vesicle docking or fusion during acrosome biogenesis (By similarity), May play a role in RNA trafficking or localization, In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm, This step is essential for HIV-1 replication.
Cellular Localization Nucleus
Tissue Specificity Ubiquitously expressed.
Swiss-Prot Key

 

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