Anti-AGTR1 Antibody

Rs. 45,619.00
SKU stj116133

General Information

Product name Anti-AGTR1 Antibody
Short Description Rabbit polyclonal to AGTR1
Description Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Type-1 angiotensin II receptorAT1ARAT1BRAngiotensin II type-1 receptorAT1
Immunogen A synthetic peptide corresponding to a sequence within amino acids 250-350 of human AGTR1 (NP_000676.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.1 kDa
Database Links
Alternative Names AGTR1Type-1 angiotensin II receptor antibodyAT1AR antibodyAT1BR antibodyAngiotensin II type-1 receptor antibodyAT1AGTR1 antibodyAGTR1A antibodyAGTR1B antibodyAT2R1 antibodyAT2R1B
Function Receptor for angiotensin II, Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Cellular Localization Cell membrane
Tissue Specificity Liver, lung, adrenal and adrenocortical adenomas
Swiss-Prot Key

 

You recently viewed

Clear recently viewed