Anti-AGTR1 antibody

Rs. 45,619.00
SKU stj22549

General Information

Product name Anti-AGTR1 antibody
Short Description Rabbit polyclonal to AGTR1
Description Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-AGTR1 antibody
Immunogen Recombinant protein of human AGTR1
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.061 kDa
Database Links
Alternative Names Type-1 angiotensin II receptor antibody
AT1AR antibody
AT1BR antibody
Angiotensin II type-1 receptor antibody
AT1 antibodyA antibodyB antibody
AT2R1 antibody
AT2R1B antibody
Function Receptor for angiotensin II, Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Cellular Localization Cell membrane
Tissue Specificity Liver, lung, adrenal and adrenocortical adenomas
Swiss-Prot Key

 

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