Anti-Ah Receptor antibody

Rs. 50,211.00
SKU stj91510

General Information

Product name Anti-Ah Receptor antibody
Short Description
Description Rabbit polyclonal to Ah Receptor.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-Ah Receptor antibody
Immunogen Synthesized peptide derived from human Ah Receptor around the non-phosphorylation site of S36.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 96 kDa
Database Links
Alternative Names Aryl hydrocarbon receptor antibody
Ah receptor antibody
AhR antibody
Class E basic helix-loop-helix protein 76 antibody
bHLHe76 antibody
BHLHE76 antibody
Function Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Cellular Localization Cytoplasm. Nucleus. Initially cytoplasmic. upon binding with ligand and interaction with a HSP90, it translocates to the nucleus.
Tissue Specificity Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle.
Swiss-Prot Key

 

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