Anti-AHCYL1 Antibody

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Rs. 34,800.00
Rs. 32,800.00
SKU stj110084

General Information

Product name Anti-AHCYL1 Antibody
Short Description Rabbit polyclonal to AHCYL1
Description The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name S-adenosylhomocysteine hydrolase-like protein 1DC-expressed AHCY-like moleculeIP(3Rs binding protein released with IP(3IRBITPutative adenosylhomocysteinase 2S-adenosyl-L-homocysteine hydrolase 2AdoHcyase 2
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 31-260 of human AHCYL1 (NP_006612.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 59 kDa
Database Links
Alternative Names AHCYL1S-adenosylhomocysteine hydrolase-like protein 1 antibodyDC-expressed AHCY-like molecule antibodyIP(3 antibodyRs binding protein released with IP(3 antibody antibodyIRBIT antibodyPutative adenosylhomocysteinase 2 antibodyS-adenosyl-L-homocysteine hydrolase 2 antibodyAdoHcyase 2AHCYL1 antibodyDCAL antibodyIRBIT antibodyXPVKONA
Function Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication, Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status, In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITPR1.
Cellular Localization Endoplasmic reticulum
Tissue Specificity Expressed in dendritic cells.
Swiss-Prot Key

 

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