Anti-AHSP Antibody

Rs. 45,619.00
SKU stj28548

General Information

Product name Anti-AHSP Antibody
Short Description Rabbit polyclonal to AHSP
Description This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-AHSP Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human AHSP (NP_057717.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 11.8 kDa
Database Links
Alternative Names AHSPAlpha-hemoglobin-stabilizing protein antibodyErythroid differentiation-related factor antibodyErythroid-associated factorAHSP antibodyEDRF antibodyERAF
Function Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development, Specifically protects free alpha-hemoglobin from precipitation, It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Cellular Localization Cytoplasm
Tissue Specificity Expressed in blood and bone marrow.
Swiss-Prot Key

 

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