Anti-AIPL1 Antibody

Rs. 45,619.00
SKU stj116048

General Information

Product name Anti-AIPL1 Antibody
Short Description Rabbit polyclonal to AIPL1
Description Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Aryl-hydrocarbon-interacting protein-like 1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human AIPL1 (NP_055151.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 43.9 kDa
Database Links
Alternative Names AIPL1Aryl-hydrocarbon-interacting protein-like 1AIPL1 antibodyAIPL2
Function May be important in protein trafficking and/or protein folding and stabilization
Cellular Localization Cytoplasm
Tissue Specificity Highly expressed in retina, specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
Swiss-Prot Key

 

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