Anti-AK4 Antibody

Rs. 45,619.00
SKU stj22562

General Information

Product name Anti-AK4 Antibody
Short Description Rabbit polyclonal to AK4
Description This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
Applications WB,IHC,IF,IP
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:100
Protein Name Anti-AK4 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human AK4 (NP_037542.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 25.3 kDa
Database Links
Alternative Names AK4Adenylate kinase 4 antibodymitochondrial antibodyAK 4AK4 antibodyAK3 antibodyAK3L1
Function Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates, Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor, Also displays broad nucleoside diphosphate kinase activity.
Cellular Localization Mitochondrion matrix
Tissue Specificity Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain.
Swiss-Prot Key

 

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