Anti-AKR1B1 Antibody

Rs. 45,619.00
SKU stj22567

General Information

Product name Anti-AKR1B1 Antibody
Short Description Rabbit polyclonal to AKR1B1
Description This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-AKR1B1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human AKR1B1 (NP_001619.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 35.9 kDa
Database Links
Alternative Names AKR1B1Aldose reductase antibodyARAKR1B1 antibodyALDR1
Function Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies
Cellular Localization Cytoplasm
Tissue Specificity Highly expressed in embryonic epithelial cells (eue) in response to osmotic stress.
Swiss-Prot Key

 

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