Anti-AKR1C1 Antibody

Rs. 45,619.00
SKU stj114973

General Information

Product name Anti-AKR1C1 Antibody
Short Description Rabbit polyclonal to AKR1C1
Description This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Applications WB
Dilution range WB 1:1000 - 1:3000
Protein Name Aldo-keto reductase family 1 member C1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C1 (NP_001344.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 36.8 kDa
Database Links
Alternative Names AKR1C1Aldo-keto reductase family 1 member C1 AKR1C1 antibodyDDH antibodyDDH1
Function Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP), In the liver and intestine, may have a role in the transport of bile, May have a role in monitoring the intrahepatic bile acid concentration, Has a low bile-binding ability, May play a role in myelin formation.
Cellular Localization Cytoplasm
Tissue Specificity Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes, highest levels found in liver, mammary gland and brain.
Swiss-Prot Key

 

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