Anti-ALDH8A1 Antibody

Rs. 61,689.00
SKU stj26334

General Information

Product name Anti-ALDH8A1 Antibody
Short Description Rabbit polyclonal to ALDH8A1
Description This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ALDH8A1 Antibody
Immunogen A synthetic peptide of human ALDH8A1
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.4 kDa
Database Links
Alternative Names ALDH8A1Aldehyde dehydrogenase family 8 member A1 ALDH8A1 antibodyALDH12
Function Converts 9-cis-retinal to 9-cis-retinoic acid, Has lower activity towards 13-cis-retinal, Has much lower activity towards all-trans-retinal, Has highest activity with benzaldehyde and decanal (in vitro), Has a preference for NAD, but shows considerable activity with NADP (in vitro).
Cellular Localization Cytoplasm
Tissue Specificity Highly expressed in adult kidney and liver, detected at lower levels in fetal liver and kidney.
Swiss-Prot Key

 

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