Anti-ALOX15 Antibody

Rs. 68,577.00
SKU stj71782

General Information

Product name Anti-ALOX15 Antibody
Short Description Goat polyclonal to ALOX15
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-ALOX15 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 74.8 kDa
Database Links
Alternative Names ALOX15Arachidonate 15-lipoxygenase antibody15-LOX antibody15-LOX-1ALOX15 antibodyLOG15
Function Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators, Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE, Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid, May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3, Probably plays an important role in the immune and inflammatory responses, Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes, In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function, May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway, Finally, it is also involved in the cellular response to IL13/interleukin-13, In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4, May also play a role in endoplasmic reticulum stress response and the regulation of bone mass,
Cellular Localization Cytoplasm, cytosol, Cell membrane
Tissue Specificity Detected in monocytes and eosinophils (at protein level), expressed in airway epithelial cells,
Swiss-Prot Key

 

You recently viewed

Clear recently viewed