Anti-ALOX5AP Antibody

Rs. 57,098.00
SKU stj29893

General Information

Product name Anti-ALOX5AP Antibody
Short Description Rabbit polyclonal to ALOX5AP
Description This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ALOX5AP Antibody
Immunogen A synthetic peptide of human ALOX5AP
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 18.2 kDa
Database Links
Alternative Names ALOX5APArachidonate 5-lipoxygenase-activating protein antibodyFLAP antibodyMK-886-binding proteinALOX5AP antibodyFLAP
Function Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase), Anchors ALOX5 to the membrane, Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5, Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Cellular Localization Nucleus membrane
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF