Anti-ALPL Antibody

Rs. 45,619.00
SKU stj22595

General Information

Product name Anti-ALPL Antibody
Short Description Rabbit polyclonal to ALPL
Description This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-ALPL Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human ALPL (NP_000469.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.3 kDa
Database Links
Alternative Names ALPLAlkaline phosphatase antibodytissue-nonspecific isozyme antibodyAP-TNAP antibodyTNSALPALPL
Function This isozyme may play a role in skeletal mineralization
Cellular Localization Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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