Anti-ANAPC1 Antibody

Rs. 45,619.00
SKU stj22606

General Information

Product name Anti-ANAPC1 Antibody
Short Description Rabbit polyclonal to ANAPC1
Description This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.
Applications WB
Dilution range WB 1:1000 - 1:2000
Protein Name Anti-ANAPC1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC1 (NP_073153.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 216.5 kDa
Database Links
Alternative Names ANAPC1Anaphase-promoting complex subunit 1 antibodyAPC1 antibodyCyclosome subunit 1 antibodyMitotic checkpoint regulator antibodyTestis-specific gene 24 proteinANAPC1 antibodyTSG24
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle, The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

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