Anti-ANGPTL3 Antibody

Rs. 45,619.00
SKU stj22611

General Information

Product name Anti-ANGPTL3 Antibody
Short Description Rabbit polyclonal to ANGPTL3
Description This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:100 - 1:200
Protein Name Anti-ANGPTL3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 231-460 of human ANGPTL3 (NP_055310.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.6 kDa
Database Links
Alternative Names ANGPTL3Angiopoietin-related protein 3 antibodyAngiopoietin-5 antibodyANG-5 antibodyAngiopoietin-like protein 3ANGPTL3 antibodyANGPT5 antibodyUNQ153/PRO179
Function Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism.
Cellular Localization Secreted
Tissue Specificity Expressed principally in liver, weakly expressed in kidney, binds to adipocytes, increased expression and colocalization with activated itgb3 in glomeruli of patients with nephrotic syndrome showing effaced podocyte foot processes (at protein level).
Swiss-Prot Key

 

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