Anti-ANKRD1 Antibody

Rs. 45,619.00
SKU stj28177

General Information

Product name Anti-ANKRD1 Antibody
Short Description Rabbit polyclonal to ANKRD1
Description The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-ANKRD1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 (NP_055206.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 36.3 kDa
Database Links
Alternative Names ANKRD1Ankyrin repeat domain-containing protein 1 antibodyCardiac ankyrin repeat protein antibodyCytokine-inducible gene C-193 protein antibodyCytokine-inducible nuclear proteinANKRD1 antibodyC193 antibodyCARP antibodyHA1A2
Function May play an important role in endothelial cell activation, May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes, Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Cellular Localization Nucleus
Tissue Specificity Mainly expressed in activated vascular endothelial cells, to a lower extent, also expressed in hepatoma cells.
Swiss-Prot Key

 

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