Anti-APLF antibody

Rs. 50,211.00
SKU stj91631

General Information

Product name Anti-APLF antibody
Short Description
Description Rabbit polyclonal to APLF.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-APLF antibody
Immunogen Synthesized peptide derived from human APLF around the non-phosphorylation site of S116.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 57 kDa
Database Links
Alternative Names Aprataxin and PNK-like factor antibody
Apurinic-apyrimidinic endonuclease APLF antibody
PNK and APTX-like FHA domain-containing protein antibody
XRCC1-interacting protein 1 antibody
C2orf13 antibody
PALF antibody
XIP1 antibody
Function Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Cellular Localization Nucleus. Cytoplasm, cytosol. Localizes to DNA damage sites. Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers.
Tissue Specificity
Swiss-Prot Key

 

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