Anti-APOA1 antibody

Rs. 73,168.00
SKU stj400012

General Information

Product name Anti-APOA1 antibody
Short Description Mouse monoclonal to APOA1
Description Apolipoprotein A1 (ApoA1) is a major component of the high-density lipoprotein complex (HDL or "good cholesterol"). ApoA1 helps to clear cholesterol from arteries. Decreased serum HDL cholesterol levels have been reported to correlate with increased risk of coronary artery disease. However, ApoA1 has been suggested as a better discrimination of coronary artery disease than HDL.
Applications ELISA
Dilution range
Protein Name Anti-APOA1 antibody
Immunogen human apolipoprotein A1 (ApoA1)
Storage Instruction 18 months from manufacturing at 2–8 °C
Type of Usage For Research Use Only (RUO).

Product Properties

Host Mouse
Clonality Monoclonal
Reactivity
Conjugation Unconjugated
Purification Purity accurate to >= 95 %
Isotype IgG1
Formulation 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative

Target

Gene ID
Gene Symbol
Molecular Weight 30.8 kDa
Database Links
Alternative Names Apolipoprotein A-I antibody
Apo-AI antibody
ApoA-I antibody
Apolipoprotein A1 antibody
Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT), As part of the SPAP complex, activates spermatozoa motility,
Cellular Localization Secreted
Tissue Specificity Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.
Swiss-Prot Key

 

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