Anti-APOA5 Antibody

Rs. 45,619.00
SKU stj22645

General Information

Product name Anti-APOA5 Antibody
Short Description Rabbit polyclonal to APOA5
Description The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
Applications IHC
Dilution range IHC 1:50 - 1:100
Protein Name Anti-APOA5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 207-366 of human APOA5 (NP_443200.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.2 kDa
Database Links
Alternative Names APOA5Apolipoprotein A-V antibodyApo-AV antibodyApoA-V antibodyApolipoprotein A5 antibodyRegeneration-associated protein 3APOA5 antibodyRAP3 antibodyUNQ411/PRO773
Function Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL, May also be associated with chylomicrons, Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity), Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
Cellular Localization Secreted
Tissue Specificity Liver and plasma.
Swiss-Prot Key

 

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