Anti-APRT Antibody

Rs. 45,619.00
SKU stj115881

General Information

Product name Anti-APRT Antibody
Short Description Rabbit polyclonal to APRT
Description Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Adenine phosphoribosyltransferaseAPRT
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 19.6 kDa
Database Links
Alternative Names APRTAdenine phosphoribosyltransferase antibodyAPRTAPRT
Function Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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