Anti-AREG Antibody

Rs. 45,619.00
SKU stj22665

General Information

Product name Anti-AREG Antibody
Short Description Rabbit polyclonal to AREG
Description The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-AREG Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 27.9 kDa
Database Links
Alternative Names AREGAmphiregulin antibodyAR antibodyColorectum cell-derived growth factor antibodyCRDGFAREG antibodyAREGB antibodySDGF
Function Ligand of the EGF receptor/EGFR, Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts
Cellular Localization Membrane
Tissue Specificity
Swiss-Prot Key

 

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